The last day of operation for Hertfordshire and West Essex ICB was 31 March 2026. The information on this website has not been updated since 31 March 2026. The legacy policies, prescribing recommendations and pathways can be accessed on this website. Find out more

Indication
Acne Vulgaris
RAG rating
Double Red
Document type
NICE technology appraisal
Place
Hertfordshire and West Essex ICB
Output type
Pharmacy / Prescribing

Clascoterone

Clascoterone (Winlevi®)

HERTFORDSHIRE AND WEST ESSEX AREA PRESCRIBING COMMITTEE (HWE APC)

Clascoterone for treating acne vulgaris
DOUBLE RED
Not recommended for prescribing by primary, community or secondary care.

Name generic (trade): Clascoterone (Winlevi®) cream
What it is: Topical androgen receptor inhibitor
Indication: Treating acne vulgaris in people 12 years and over
Date of decision: December 2025
NICE: NICE TA1105 – Terminated appraisal

HWE APC recommendation:
Treatment appraisal terminated by NICE. 

HWE APC designated a "double red” category - Not recommended for prescribing in primary, community or secondary care.  

NICE is unable to make a recommendation on clascoterone (Winlevi®) for treating acne vulgaris in people 12 years and over. The company (manufacturer) did not provide an evidence submission. 

Version number
1.0
Developed by
Pharmacy and Medicines Optimisation Team, Hertfordshire and West Essex (HWE) ICB with relevant HWE ICS stakeholders.
Approved by
Hertfordshire & West Essex Area Prescribing Committee
Date approved / updated
December 2025
Review date
This HWE APC recommendation is based upon the evidence available at the time of publication. This recommendation will be reviewed upon request in the light of new evidence becoming available.
Superseded version
NA
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